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Abstract. This study porpose to examine the effect of job stress on job satisfaction, job stress on organizational commitment, Job Satisfaction to organizational commitment, stress work to move intention, job satisfaction to move intention, organizational commitment to move intention, indirect influence between work stress Organizational commitment to job satisfaction, job stress on. The sample in this research is 40 medical representatives of PT. Pharmaceutical Industry Gracia Pharmindo Branch of North Sumatra, Technique of completion of this research data using the interview, and questionnaire. Data analysis technique used is Path Analysis. The results of this study indicate job stress and negativity to the significance of job satisfaction and commitment to organizational commitment, significant and significant work stress on shifting intentions, job satisfaction and commitment to shifting intentions, positive and significant hard work towards turnover intention commitment through job satisfaction, stress significant and significant work on turnover intention through commitment of organization Keywords: Job Stress, Job Satisfaction, Organizational Commitment, Turnover Intention
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