Deterrents in recruitment of COVID‐19 convalescent plasma donors: Experience from a hospital‐based blood centre in India

Yashaswi Dhiman · Poonam Coshic · Hem Chandra Pandey · Basanta Khatiwada · Sanjay Kumar Gupta

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Blood donation and transfusion practices Ethics in Clinical Research Organ Donation and Transplantation

Abstract

INTRODUCTION: Recruitment of Covid-19 convalescent plasma (CCP) donors may present as a challenge due to inexperience and differences in donor profile as compared to whole blood donation. Present study highlights the deterrents to recruiting CCP donors at a hospital based blood centre. MATERIALS AND METHODS: Potential CCP donors were contacted individually by telephone and a group approach through camp organisers from May to July 2020. Recruitment challenges were noted and deferrals of these recruited donors during screening and medical examination was obtained and analysed. RESULTS: Total 1165 potential CCP donors were contacted. Around 47% donors were lost due to challenges related to information storage and retrieval. Fear of health, family pressure, and fear of a new procedure were major reason (27.2%) for unwillingness to donate. The main reasons for deferral among potential donors were multiparity (38%) and being overage/underage (31.6%). Finally, 468 donors were recruited including 408 by individual approach and 60 by a group approach. From these absence of detectable COVID-19 antibodies were found in 15.4%. Few donors (9.0%) were deferred as they had not completed 28 days post recovery. CONCLUSION: The process of CCP donor recruitment differs from that of whole blood donation and requires an individualised approach with involvement of clinicians in the initial phases of the pandemic. A group approach targeting specific organisations could be adopted for a successful CCP collection program. There is a need to relook into some aspects of donor selection such as consideration of multiparous female donors and overage/underage donors after reviewing scientific evidence.

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1992Volunteers' motivations: A functional strategy for the recruitment, placement, and retention of volunteers 2020Guidance for the procurement of COVID‐19 convalescent plasma: differences between high‐ and low‐middle‐income countries 2010Practical limitations of convalescent plasma collection: a case scenario in pandemic preparation for influenza A (H1N1) infection 2020“Because Every Drop Counts”: Blood donation during the COVID-19 Pandemic 2020Dwindling blood reserves: An ominous downside of COVID-19 pandemic

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