COVID-19 vaccine uptake and intention during pregnancy in Canada

Laura Reifferscheid · Emmanuel Akwasi Marfo · Ali Assi · Ève Dubé · Noni E. MacDonald · Samantha B. Meyer +9 more

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Vaccine Coverage and Hesitancy SARS-CoV-2 and COVID-19 Research COVID-19 and Mental Health

Abstract

OBJECTIVE: To investigate COVID-19 vaccine uptake and intent among pregnant people in Canada, and determine associated factors. METHODS: We conducted a national cross-sectional survey among pregnant people from May 28 through June 7, 2021 (n = 193). Respondents completed a questionnaire to determine COVID-19 vaccine acceptance (defined as either received or intend to receive a COVID-19 vaccine during pregnancy), factors associated with vaccine acceptance, and rationale for accepting/not accepting the vaccine. RESULTS: Of 193 respondents, 57.5% (n = 111) reported COVID-19 vaccine acceptance. Among those who did not accept the vaccine, concern over vaccine safety was the most commonly cited reason (90.1%, n = 73), and 81.7% (n = 67) disagreed with receiving a vaccine that had not been tested in pregnant people. Confidence in COVID-19 vaccine safety (aOR 16.72, 95% CI: 7.22, 42.39), Indigenous self-identification (aOR 11.59, 95% CI: 1.77, 117.18), and employment in an occupation at high risk for COVID-19 exposure excluding healthcare (aOR 4.76, 95% CI: 1.32, 18.60) were associated with vaccine acceptance. Perceived personal risk of COVID-19 disease was not associated with vaccine acceptance in the multivariate model. CONCLUSION: Vaccine safety is a primary concern for this population. Safety information should be communicated to this population as it emerges, along with clear messaging on the benefits of vaccination, as disease risk is either poorly understood or poorly valued in this population.

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References

2004Improving the Quality of Web Surveys: The Checklist for Reporting Results of Internet E-Surveys (CHERRIES)2018Beyond confidence: Development of a measure assessing the 5C psychological antecedents of vaccination 2021COVID-19 vaccine acceptance among pregnant women and mothers of young children: results of a survey in 16 countries 2014Determinants of uptake of influenza vaccination among pregnant women – A systematic review 2021Covid-19 vaccine acceptance, hesitancy, and refusal among Canadian healthcare workers: A multicenter survey 2022Women’s views on accepting COVID-19 vaccination during and after pregnancy, and for their babies: a multi-methods study in the UK 2021COVID-19 Vaccination Coverage Among Pregnant Women During Pregnancy — Eight Integrated Health Care Organizations, United States, December 14, 2020–May 8, 2021 2021Encouraging COVID-19 Vaccine Uptake Through Effective Health Communication

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2024A scoping review of global COVID-19 vaccine hesitancy among pregnant persons 2022“We need to protect each other”: COVID-19 vaccination intentions and concerns among Racialized minority and Indigenous Peoples in Canada 2022COVID-19 Vaccination and Related Determinants of Hesitancy among Pregnant Women: A Systematic Review and Meta-Analysis

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