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This study aimed to determine the relationship between job satisfaction, work-life balance, and retention of generation Y support staff during the COVID-19 pandemic in Thailand. The questionnaire used for this study consisted of 4 parts: 1) personal characteristics; 2) job satisfaction; 3) work-life balance; and 4) employee retention. Data for this cross-sectional study was collected between March 10 to April 17, 2022. The study includes 962 participants, of whom 544 were recruited using a stratified sampling method. SPSS version 18 was used to analyze the data, and the statistical analysis included descriptive statistics, Pearson's product-moment correlation, and stepwise multiple regression. The result showed that job satisfaction, work-life balance, and employee retention mean scores were moderate. Age, income adequacy, job satisfaction, and work-life balance significantly correlated with the retention of generation Y staff. Moreover, job satisfaction and work-life balance were statistically significant predictors and predicted 57.1% retention of generation Y support staff. These results suggest that the Faculty of Dentistry should focus on improving job satisfaction and work-life balance for generation Y support staff to prevent them from leaving the organization.
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