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Integrated therapist and online cognitive behavioural therapy in addition to usual care versus usual care for depression in primary care in England (INTERACT): a two-group, parallel, multicentre, randomised controlled trial
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Integrated therapist and online cognitive behavioural therapy in addition to usual care versus usual care for depression in primary care in England (INTERACT): a two-group, parallel, multicentre, randomised controlled trial (2026)Integrated therapist and online cognitive…Psychological treatment of depression: A systematic overview of a ‘Meta-Analytic Research Domain’ (2023)Psychological treatment of de…How much change is enough? Evidence from a longitudinal study on depression in UK primary care (2020)How much change is enough? Ev…The process and delivery of CBT for depression in adults: a systematic review and network meta-analysis (2019)The process and delivery of C…Effectiveness and Acceptability of Cognitive Behavior Therapy Delivery Formats in Adults With Depression (2019)Effectiveness and Acceptabili…Cost and Effectiveness of Blended Versus Standard Cognitive Behavioral Therapy for Outpatients With Depression in Routine Specialized Mental Health Care: Pilot Randomized Controlled Trial (2019)Cost and Effectiveness of Ble…Telephone-supported computerised cognitive–behavioural therapy: REEACT-2 large-scale pragmatic randomised controlled trial (2017)Telephone-supported computeri…Efficacy of Self-guided Internet-Based Cognitive Behavioral Therapy in the Treatment of Depressive Symptoms (2017)Efficacy of Self-guided Inter…Application of Synchronous Text-Based Dialogue Systems in Mental Health Interventions: Systematic Review (2017)Application of Synchronous Te…Realizing the Potential of Behavioral Intervention Technologies (2013)Realizing the Potential of Be…Effect of Telephone-Administered vs Face-to-face Cognitive Behavioral Therapy on Adherence to Therapy and Depression Outcomes Among Primary Care Patients (2012)Effect of Telephone-Administe…The Relationship Between Homework Compliance and Therapy Outcomes: An Updated Meta-Analysis (2010)The Relationship Between Home…Therapist-delivered internet psychotherapy for depression in primary care: a randomised controlled trial (2009)Therapist-delivered internet …A Brief Measure for Assessing Generalized Anxiety Disorder (2006)A Brief Measure for Assessing…The Work and Social Adjustment Scale: a simple measure of impairment in functioning (2002)The Work and Social Adjustmen…The PHQ-9 (2001)The PHQ-9Assessing psychiatric disorder with a human interviewer or a computer. 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Hedges and Ingram Olkin New York: Academic Press, 1985. xxii + 369 pp (1988)mHealth: A Mechanism to Deliver More Accessible, More Effective Mental Health Care (2013)Methods of Meta-Analysis: Correcting Error and Bias in Research Findings (2015)Quantity and Quality of Homework Compliance: A Meta-Analysis of Relations With Outcome in Cognitive Behavior Therapy (2016)The Processes of Cognitive Behavioral Therapy: A Review of Meta-Analyses (2018)EuroQol - a new facility for the measurement of health-related quality of life (1990)Measuring psychiatric disorder in the community: a standardized assessment for use by lay interviewers (1992)The Epidemiology of Major Depressive Disorder (2003)Computer Therapy for the Anxiety and Depressive Disorders Is Effective, Acceptable and Practical Health Care: A Meta-Analysis (2010)Computer-based psychological treatments for depression: A systematic review and meta-analysis (2012)Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide (2014)An Inventory for Measuring Depression (1961)A New Depression Scale Designed to be Sensitive to Change (1979)Validation and Utility of a Self-report Version of PRIME-MD The PHQ Primary Care Study (1999)The PHQ-9: A New Depression Diagnostic and Severity Measure (2002)The Patient Health Questionnaire-2 (2003)The CES-D Scale (1977)Assessing Risk of Bias in Included Studies (2008)An Empathy-Driven, Conversational Artificial Intelligence Agent (Wysa) for Digital Mental Well-Being: Real-World Data Evaluation Mixed-Methods Study (2018)Barriers to and Facilitators of User Engagement With Digital Mental Health Interventions: Systematic Review (2021)Time for united action on depression: a Lancet–World Psychiatric Association Commission (2022)Establishing and maintaining long-term human-computer relationships (2005)Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement (2009)Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation (2015)A fully automated conversational agent for promoting mental well-being: A pilot RCT using mixed methods (2017)Artificially intelligent chatbots in digital mental health interventions: a review (2021)The Hospital Anxiety and Depression Scale (1983)Psychotherapy for Depression Across Different Age Groups: A Systematic Review and Meta-analysis (2020)Internet-Based Cognitive Behavioral Therapy for Depression (2021)The Measurement of Observer Agreement for Categorical Data (1977)Comparison of Beck Depression Inventories-IA and-II in Psychiatric Outpatients (1996)Effective dose 50 method as the minimal clinically important difference: Evidence from depression trials (2021)Efficacy and effectiveness of therapist-guided internet versus face-to-face cognitive behavioural therapy for depression via counterfactual inference using naturalistic registers and machine learning in Finland: a retrospective cohort study (2025)Generalized Anxiety Disorder 7-item (GAD-7) and 2-item (GAD-2) scales for detecting anxiety disorders in adults (2025)
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References

  • 2001The PHQ-945,536 cited
  • 2006A Brief Measure for Assessing Generalized Anxiety Disorder32,255 cited
  • 2002The Work and Social Adjustment Scale: a simple measure of impairment in functioning2,523 cited
  • 2017Efficacy of Self-guided Internet-Based Cognitive Behavioral Therapy in the Treatment of Depressive Symptoms719 cited
  • 2019Effectiveness and Acceptability of Cognitive Behavior Therapy Delivery Formats in Adults With Depression563 cited
  • 2009Therapist-delivered internet psychotherapy for depression in primary care: a randomised controlled trial402 cited
  • 2012Effect of Telephone-Administered vs Face-to-face Cognitive Behavioral Therapy on Adherence to Therapy and Depression Outcomes Among Primary Care Patients334 cited
  • 2010The Relationship Between Homework Compliance and Therapy Outcomes: An Updated Meta-Analysis307 cited
  • 2017Application of Synchronous Text-Based Dialogue Systems in Mental Health Interventions: Systematic Review277 cited
  • 2020How much change is enough? Evidence from a longitudinal study on depression in UK primary care163 cited
  • 2019The process and delivery of CBT for depression in adults: a systematic review and network meta-analysis161 cited
  • 2013Realizing the Potential of Behavioral Intervention Technologies152 cited
  • 1994Assessing psychiatric disorder with a human interviewer or a computer.150 cited

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2023
Psychological treatment of depression: A systematic overview of a ‘Meta-Analytic Research Domain’
136 cited
  • 2017Telephone-supported computerised cognitive–behavioural therapy: REEACT-2 large-scale pragmatic randomised controlled trial116 cited
  • 2019Cost and Effectiveness of Blended Versus Standard Cognitive Behavioral Therapy for Outpatients With Depression in Routine Specialized Mental Health Care: Pilot Randomized Controlled Trial83 cited
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