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Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration
4 references·16 citing·35 second hop
Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration (1988)Toxic effects of MDMA on central serotone…(+/-)3,4-Methylenedioxymethamphetamine selectively damages central serotonergic neurons in nonhuman primates (1988)(+/-)3,4-Methylenedioxymetham…Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine. (1987)Neurotoxicity of the psychede…Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain. (1987)Biochemical and histological …Hallucinogenic Amphetamine Selectively Destroys Brain Serotonin Nerve Terminals (1985)Hallucinogenic Amphetamine Se…Effects of MDMA on sociability and neural response to social threat and social reward (2009)Effects of MDMA on sociabilit…Ecstasy: Are animal data consistent between species and can they translate to humans? (2006)Ecstasy: Are animal data cons…Acute and long-term effects of MDMA on cerebral dopamine biochemistry and function (2004)Acute and long-term effects o…Reduced cortical gray matter density in human MDMA (Ecstasy) users: a voxel-based morphometry study (2003)Reduced cortical gray matter …Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanisms (2003)Methylenedioxymethamphetamine…3,4-Methylenedioxymethamphetamine (Ecstasy)-Induced Learning and Memory Impairments Depend on the Age of Exposure during Early Development (2001)3,4-Methylenedioxymethampheta…Long-lasting effects of (±)3,4-methylene-dioxymethamphetamine (Ecstasy) on serotonin system function in humans (2000)Long-lasting effects of (±)3,…Is MDMA (‘Ecstasy’) Neurotoxic in Humans? An Overview of Evidence and of Methodological Problems in Research (2000)Is MDMA (‘Ecstasy’) Neurotoxi…Effect of ecstasy [3,4-methylenedioxymethamphetamine (MDMA)] on cerebral blood flow: a co-registered SPECT and MRI study (2000)Effect of ecstasy [3,4-methyl…3,4-Methylenedioxy analogues of amphetamine: Defining the risks to humans (1999)3,4-Methylenedioxy analogues …The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA (`ecstasy') (1998)The relationship between the …In vivo detection of short- and long-term MDMA neurotoxicity?a positron emission tomography study in the living baboon brain (1998)In vivo detection of short- a…Adverse Reactions with 3,4-Methylenedioxymethamphetamine (MDMA; ???Ecstasy???) (1996)Adverse Reactions with 3,4-Me…Lasting Neuropsychiatric Sequelae of (??)Methylenedioxymethamphetamine (???Ecstasy???) in Recreational Users (1991)Lasting Neuropsychiatric Sequ…Chronic paranoid psychosis after misuse of MDMA ("ecstasy") (1991)Chronic paranoid psychosis af…Neurochemistry and Neurotoxicity of 3,4‐Methylenedioxymethamphetamine (MDMA, “Ecstasy”) (1990)Neurochemistry and Neurotoxic…3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites. (1987)In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain (1987)MDMA-induced neurotoxicity: Parameters of degeneration and recovery of brain serotonin neurons (1988)The relative contributions of ecstasy and cannabis to cognitive impairment (2000)The pharmacology of the acute hyperthermic response that follows administration of 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) to rats (2002)Chronic tolerance to recreational MDMA (3,4-methylenedioxymethamphetamine) or Ecstasy (2005)Differences Between the Mechanism of Action of MDMA, MBDB, and the Classic Hallucinogens. Identification of a New Therapeutic Class: Entactogens (1986)The health effects of ecstasy: a literature review (2002)The pre-clinical behavioural pharmacology of 3,4-methylenedioxymethamphetamine (MDMA) (2003)MDMA (3,4-Methylenedioxymethamphetamine) or Ecstasy: The Neuropsychobiological Implications of Taking It at Dances and Raves (2004)Positron emission tomographic evidence of toxic effect of MDMA (“Ecstasy”) on brain serotonin neurons in human beings (1998)The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) (2003)3,4‐methylenedioxymethamphetamine (MDMA) administration to rats decreases brain tissue serotonin but not serotonin transporter protein and glial fibrillary acidic protein (2004)Memory deficit and reduced anxiety in young adult rats given repeated intermittent MDMA treatment during the periadolescent period (2004)Dark Classics in Chemical Neuroscience: 3,4-Methylenedioxymethamphetamine (2018)Profile of mood states (1992)DSM-IV: Diagnostic and Statistical Manual of Mental Disorders (1994)Oxytocin increases trust in humans (2005)The Effects of Acutely Administered 3,4-Methylenedioxymethamphetamine on Spontaneous Brain Function in Healthy Volunteers Measured with Arterial Spin Labeling and Blood Oxygen Level–Dependent Resting State Functional Connectivity (2014)Clinical applications of hallucinogens: A review. (2016)Breakthrough for Trauma Treatment: Safety and Efficacy of MDMA-Assisted Psychotherapy Compared to Paroxetine and Sertraline (2019)Recreational MDMA use in Sydney: a profile of ‘Ecstasy’ users and their experiences with the drug (1992)Psychological and Cardiovascular Effects and Short-Term Sequelae of MDMA (“Ecstasy”) in MDMA-Naïve Healthy Volunteers (1998)Ecstasy (MDMA): a review of its possible persistent psychological effects (2000)Psychobiologic effects of 3,4-methylenedioxymethamphetamine in humans: methodological considerations and preliminary observations (1995)The Acute and Chronic Effects of MDMA (“Ecstasy”) on Cortical 5-HT2A Receptors in Rat and Human Brain (2002)Acute, sub‐acute and long‐term subjective consequences of ‘ecstasy’ (MDMA) consumption in 430 regular users (2003)Subjective effects of 3,4-methylenedioxymethamphetamine in recreational users. (1988)Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research (2001)Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity (2002)3,4‐Methylenedioxymethamphetamine (MDMA, “Ecstasy”): pharmacology and toxicology in animals and humans (1994)(±)3,4-Methylenedioxymethamphetamine (‘Ecstasy’)-Induced Serotonin Neurotoxicity: Studies in Animals (2000)Molecular and Cellular Mechanisms of Ecstasy-Induced Neurotoxicity: An Overview (2009)A review of acute effects of 3,4-methylenedioxymethamphetamine in healthy volunteers (2006)Dose-Response Study of N,N-Dimethyltryptamine in Humans (1994)
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References

  • 1987Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine.530 cited
  • 1987Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain.453 cited
  • 1985Hallucinogenic Amphetamine Selectively Destroys Brain Serotonin Nerve Terminals367 cited
  • 1988(+/-)3,4-Methylenedioxymethamphetamine selectively damages central serotonergic neurons in nonhuman primates300 cited

Cited by

  • 1998The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA (`ecstasy')242 cited
  • 2009Effects of MDMA on sociability and neural response to social threat and social reward206 cited
  • 2003Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanisms199 cited
  • 1990Neurochemistry and Neurotoxicity of 3,4‐Methylenedioxymethamphetamine (MDMA, “Ecstasy”)183 cited
  • 19993,4-Methylenedioxy analogues of amphetamine: Defining the risks to humans178 cited
  • 2004Acute and long-term effects of MDMA on cerebral dopamine biochemistry and function153 cited
  • 1998In vivo detection of short- and long-term MDMA neurotoxicity?a positron emission tomography study in the living baboon brain145 cited
  • 20013,4-Methylenedioxymethamphetamine (Ecstasy)-Induced Learning and Memory Impairments Depend on the Age of Exposure during Early Development143 cited
  • 2000

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Is MDMA (‘Ecstasy’) Neurotoxic in Humans? An Overview of Evidence and of Methodological Problems in Research
142 cited
  • 2000Long-lasting effects of (±)3,4-methylene-dioxymethamphetamine (Ecstasy) on serotonin system function in humans138 cited
  • 1991Lasting Neuropsychiatric Sequelae of (??)Methylenedioxymethamphetamine (???Ecstasy???) in Recreational Users134 cited
  • 2003Reduced cortical gray matter density in human MDMA (Ecstasy) users: a voxel-based morphometry study132 cited
  • 1991Chronic paranoid psychosis after misuse of MDMA ("ecstasy")127 cited
  • 2006Ecstasy: Are animal data consistent between species and can they translate to humans?126 cited
  • 1996Adverse Reactions with 3,4-Methylenedioxymethamphetamine (MDMA; ???Ecstasy???)123 cited
  • 2000Effect of ecstasy [3,4-methylenedioxymethamphetamine (MDMA)] on cerebral blood flow: a co-registered SPECT and MRI study121 cited