Poor-Quality Medical Research

Douglas G. Altman

33 citations0/0 files storedJAMA

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Meta-analysis and systematic reviews Academic Publishing and Open Access Academic integrity and plagiarism

Abstract

The aim of medical research is to advance scientific knowledge and hence—directly or indirectly—lead to improvements in the treatment and prevention of disease. Each research project should continue systematically from previous research and feed into future research. Each project should contribute beneficially to a slowly evolving body of research. A study should not mislead; otherwise it could adversely affect clinical practice and future research. In 1994 I observed that research papers commonly contain methodological errors, report results selectively, and draw unjustified conclusions. Here I revisit the topic and suggest how journal editors can help.

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References

2000Meta-analysis of Observational Studies in Epidemiology A Proposal for Reporting 1999Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement 2001The Revised CONSORT Statement for Reporting Randomized Trials: Explanation and Elaboration 2001Assessing the quality of controlled clinical trials 2001The CONSORT Statement: Revised Recommendations for Improving the Quality of Reports of Parallel-Group Randomized Trials 1994The scandal of poor medical research 1999Clinical Epidemiological Quality in Molecular Genetic Research 1997Putting trials on trial--the costs and consequences of small trials in depression: a systematic review of methodology.

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2003The editorial process for medical journals: I. Introduction of a series and discussion of the responsibilities of editors, authors, and reviewers 2005The Performance of Peer Review and a Beauty Contest of Referee Processes of Economics Journals

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